Big Brain Holdings Invests in Seed, Pre-Seed and Early Stage Startups

Big Brain Holdings

United States of America

Protocol Labs is a research, development, and deployment lab for network protocols.

Protocol Labs

No Limit Holdings

Avalanche VC is an early-stage technology investor in massive trends.

Avalanche VC

Filecoin

Akave

Blockchange Ventures is an investing firm that invest in early-stage blockchain companies, protocols, and applications.

Blockchange Ventures

Lightshift Capital

Blockchain Builders Fund

Switzerland

Traditional VC investor into digital assets. We invest globally into outstanding founders building next generation of financial services.

RockawayX

Disruptive crypto-native fund focused on early-stage protocols and fueled by OGs, founders, and key investors.

Dewhales

Duplicate Capital

Vistula Capital

Nucleus

dumpster

HyperLend

Managed by the family office of Arthur Hayes (co-founder, BitMEX), Maelstrom is building a long-term portfolio of infrastructure companies that will serve as the foundation of the next wave of trustless decentralization.

Maelstrom

Dispersion Capital

Escape Velocity

ARO Network

Amber Group is a one-stop crypto finance service provider that provides liquidity provision, trading and asset management services 24/7.

Amber Group

Singapore

NGC Ventures is one of the largest institutional investors of blockchain technologies, and has been a key contributor to a number of leading projects.

NGC Ventures

Hivemind Capital Partners

Protagonist is a crypto fund and incubation lab supporting foundational protocols in emerging blockchain ecosystems.

Protagonist

Paul Taylor

echo

Silhouette

Arrington Capital is a thesis-focused digital asset and Web3 investing firm. Since 2017, Arrington Capital has invested in over 200 early-stage companies in the crypto ecosystem. Arrington Capital's crypto-native team of seasoned entrepreneurs, founders, and executives is committed to doubling down on efforts to ensure our partners' success.

Arrington Capital

Coinbase Ventures is the venture capital arm of Coinbase, one of the largest and most well-known cryptocurrency exchanges in the world. Coinbase Ventures is focused on investing in early-stage companies and projects in the blockchain and cryptocurrency space. It provides funding, resources, and support to startups and entrepreneurs working on innovative blockchain and crypto-related technologies and applications.

Coinbase Ventures

gumi Cryptos Capital is a blockchain and cryptographic asset fund that invests in the crypto native stack from L1 to the application layer, as well as in traditional businesses supporting the ecosystem.

gumi Cryptos Capital

Hong Kong

Animoca Brands is a global digital entertainment company that specializes in the development and publishing of mobile games, blockchain-based games, and non-fungible tokens (NFTs). They are known for creating and publishing a wide range of popular games, including licensed intellectual properties such as Formula 1, Doraemon, and MotoGP. Animoca Brands is also heavily involved in the blockchain gaming space, leveraging the benefits of blockchain technology and NFTs to create unique gaming experiences.

Animoca Brands

Robot Ventures primarily invests in projects and companies related to decentralized finance (DeFi), blockchain technology, cryptocurrencies, and the broader Web 3.0 ecosystem. They seek to identify promising early-stage projects that are building innovative solutions in these areas.

Robot Ventures

Netherlands

Venture Capital Fund in Blockchain & Distributed Ledger Technology (DLT)

Maven 11 Capital

SCB Limited

Resolv Labs

Framework Ventures is a cutting-edge venture capital firm deeply immersed in the world of decentralized finance (DeFi) and blockchain technology. Founded by Michael Anderson and Vance Spencer, Framework Ventures stands out as a key player in the rapidly evolving landscape of digital assets and blockchain-based financial innovations.

Framework Ventures

Selini is a global trading firm focused on systematic trading, liquidity provision, efficient execution, and venture investing—all within the digital assets space.

Selini Capital

Citizen X is a thesis-driven venture fund investing in Web 3.0 and decentralized technologies.

CitizenX Crypto Ventures Fund, L.P.

Rubik Ventures

Symbolic Capital is a crypto-native fund founded by web3 founders.

Symbolic Capital

AlfaDAO

Auros is an algorithmic trading and market making firm that delivers best-in-class liquidity for exchanges and token projects.

Auros Global

Decima

Baboon VC

TempleDAO

Halo Capital

Infrared BGT

Malta

YZi Labs is an investment firm formerly known as Binance Labs that invests in all stages of development in the fields of Web3, artificial intelligence (AI), and biotechnology.

YZi Labs (prev Binance Labs)

Tribe Capital is a venture capital firm with over $1.6 billion in assets under management that focuses on using product science and data to design N-of-1 companies and investments.

Tribe Capital

Signum Capital invests in distributed ledger technologies and crypto assets. Signum Capital support game-changing projects that advance us towards the future of blockchain-enabled socioeconomic transformation.

Signum Capital

Shima Capital is an early stage VC firm investing in disruptive web3 and blockchain technology companies.

Shima Capital

DCF GOD

Tenzor Capital

Mr.Block is a blockchain community that creates a connection between international projects and another country.

Mr. Block

Alex Shin

DoraHacks Ventures

dao5

Oak Grove Ventures is an early-stage investment firm with a primary focus on advanced technology sectors.

Oak Grove Ventures

Synergis has made 10 investments so far, the most recent investment project is Hibiki Run, and the investment announcement time is July 24, 2023

According to the CoinCarp fundraising database, Synergis has invested in 4 Web3 projects, 2 NFTs projects, 1 DeFi projects and 1 Others projects. Among all, 50% of Synergis's investments are Web3 projects.

Synergis

Ouroboros Capital

China

Early stage venture capital fund focusing on Asia/US cross-border technology investments.

Draper Dragon

MH Ventures is a world-class community-backed venture capital investing in top blockchain projects of the future.

MH Ventures

Caladan (Alphalab)

Crypto-native venture capital that invests in community-driven Web3 startups.

Lecca Ventures

Tané is committed to contributing to the crypto/Web3 ecosystem by leveraging experience and knowledge by developing and investing in web businesses and applications.

Tané

Paramita Venture

Reforge VC

Syntax Capital is a multi-strategy digital asset investment firm focused on liquid strategies & early-stage venture. Legacy venture arm: Aves Lair.

Syntax Capital

57Blocks

IMUA (Prev. Exocore)

Pantera Capital is a blockchain and cryptocurrency-focused investment firm and hedge fund. It was founded in 2013 by Dan Morehead, who is a former Wall Street executive and chief financial officer (CFO) at Tiger Management. Pantera Capital is known for being one of the earliest institutional investors in the cryptocurrency space and has been actively involved in supporting the growth and development of blockchain technology and digital assets.

Pantera Capital

Digital Currency Group builds and supports bitcoin and blockchain companies by leveraging insights, network, and access to capital.

Digital Currency Group (DCG)

Founders Fund is a venture capital firm based in San Francisco, specializing in investments in science and technology companies.

Founders Fund

Archetype is an early-stage venture fund focused on accelerating the decentralized future.

Archetype

Altius

BitScale Capital invests in teams and solutions that bring transparency and efficiency to our world through cutting-edge technology.

BitScale Capital

The Spartan Group primarily focuses on investments in digital assets, cryptocurrencies, and blockchain-related projects. They actively manage a portfolio of various cryptocurrencies, including Bitcoin and Ethereum, as well as other tokens and blockchain assets.

The Spartan Group

OKX Ventures is a fund focused on exploring high-quality and promising projects, with an initial capital of $100 million.

OKX Ventures

United Kingdom

Wintermute is a truly value adding investor dedicated to supporting the innovation in the blockchain ecosystem.

Wintermute

The Open Platform

Blum

Lemniscap is an investment firm specializing in investments in emerging cryptoassets and blockchain companies

Lemniscap

P-OPS TEAM is a decentralized organization providing you with validation and staking services, blockchain consultation, growth acceleration and investment capital for innovative Web 3.0 projects.

P-OPS Team

Borderless Capital is a Blockchain VC firm and a modern financial institution investing capital and co-building financial products with our portfolio companies that accelerates access, bootstraps adoption, and creates value globally through the Algorand Borderless Economy.

Borderless Capital

Chorus One is building validation and staking infrastructure for Proof-of-Stake networks.

Chorus One

Race Capital

Finality Capital Partners

Flowdesk

Termina

HashKey Capital is a blockchain and cryptocurrency-focused venture capital and investment firm based in Hong Kong. They specialize in funding and supporting early-stage blockchain and cryptocurrency projects, startups, and companies.

HashKey Capital

Flori Ventures

w3.fund

Verda Ventures is a venture fund focused on backing blockchain-enabled companies contributing to the evolution of global financial infrastructure.

Verda Ventures

T Capital

Richard Parsons

Mento

Blockchain Capital is a venture capital firm specializing in investments in blockchain technology and cryptocurrencies. It was founded in 2013 by Bart Stephens and Brad Stephens, and it's headquartered in San Francisco, California. Blockchain Capital is one of the earliest and most well-known venture capital firms dedicated exclusively to the blockchain and cryptocurrency space.

Blockchain Capital

CMS Holdings may also invest in early-stage blockchain and cryptocurrency projects through private investments and strategic partnerships. They provide capital and support to innovative startups in the crypto space.

CMS Holdings

Bankless

Cadenza actively invests in the technology companies and related crypto assets that are reshaping financial services.

Cadenza Ventures

Breed VC is an early stage crypto venture fund dedicated to helping the top founders build the decentralized future

Breed

Base is a secure, low-cost, builder-friendly Ethereum L2 built to bring the next billion users onchain.

Base Ecosystem Fund

Zach Segal

Tommy Shaughnessy

Isaiah Washington

HTX Venture, the global investment arm of HTX, integrates investment, incubation, and research to identify the best and brightest teams in the world.

HTX Ventures (previously Huobi Ventures)

RISE

Sky9 Capital is a leading venture capital fund dedicated to supporting disruptive technologies and outstanding innovators.

Sky9

UOB Venture Management

Calvin Liu

Nomad Capital

Interop Ventures is an early-stage venture fund concentrating on the rapidly evolving Interchain ecosystem, a network of interconnected decentralized applications built on the Cosmos technology stack.

Interop

Dora Factory

An investment company specialized in Blockchain sector. Up to now, they've invested over 100 blockchain projects in their portfolio. The most successful investments includes Coinbase, Binance, Canaan, etc.

Fundamental Labs

Spark Digital Capital is a research-focused crypto fund that invests in the future of blockchain and technology.

Spark Digital Capital

LAO is a member-led venture fund built on the spirit of Ethereum’s original DAO. As a global collective of Ethereum enthusiasts and experts, LAO invests in early-stage projects that push the boundaries of DeFi, NFTs, privacy, and Web3 social applications.

The Lao

Hypersphere is a crypto-native investment platform designed to partner with early-stage and public blockchain networks.

Hypersphere Ventures

SevenX Ventures provides insights and operational expertise to help blockchain startups in growing.

SevenX Ventures

Gate.io

JRR is a Fin-tech group focused exclusively on disruptive innovations related to the traditional industry, which is the bridge connecting real world and digital asset.

JRR Group

LongHash Ventures is a global blockchain accelerator and VC fund.

LongHash Ventures

Lotus Capital is the leading crypto fund in the Middle East. An ecosystem of entrepreneurs, engineers, researchers and scientists.

Lotus capital

AU21 Capital was founded by Chandler Guo and Kenzi Wang in 2017 with the mission of backing the most promising blockchain entrepreneurs, and providing founders with resources and connections to succeed.

AU21 Capital

DRF focuses on building a real open web with top teams.

Digital Renaissance

SNZ Holding is a crypto fund founded by a group of engineers, blockchain evangelists and entrepreneurs passionate about disruptive blockchain technologies.

SNZ Holding

Investing in the digital transformation wave of blockchain technology. Enthusiastic participator in public welfare and industrial ecology.

			Tahap	Investor
Akave	$6.65 M	~$66.50 M	Seed Round	+2		Layer-2	Mar 2, 2026
HPL HyperLend	$1.70 M	~$17.00 M	Funding Round	+5		Lending Platform	Jan 19, 2026
ARO Network	$2.10 M	~$21.00 M	Pre-seed	+1		Blockchain Service	Jul 28, 2025
Silhouette	$3.00 M	~$30.00 M	Pre-seed	+5		DEX	Jun 10, 2025
RESOLV Resolv Labs	$10.00 M	~$100.00 M	Seed Round	+5		Stablecoin Issuer	Apr 16, 2025
IBGT Infrared BGT	$14.00 M	~$140.00 M	Series A	+11		DeFi	Mar 4, 2025
IMUA (Prev. Exocore)	$5.00 M	~$50.00 M	Seed Round	+7		Blockchain	Feb 24, 2025
Altius	$11.00 M	~$110.00 M	Pre-seed	+4		Infrastructure	Feb 18, 2025
BLUM Blum	$5.00 M	~$50.00 M	Seed Round	+5		DeFi	Feb 12, 2025
Termina	$4.00 M	~$40.00 M	Seed Round	+7		Infrastructure	Oct 30, 2024
Mento	$10.00 M	~$100.00 M	Funding Round	+4		DeFi	Oct 16, 2024
BSX BSX	$4.00 M	~$40.00 M	Seed Round	+8		Perpetual	Aug 21, 2024
DORA Dora Factory	--	--	Strategic Round	+4		Infrastructure	May 23, 2024
BLESS Bless	$5.00 M	~$50.00 M	Seed Round	+2		Infrastructure	May 20, 2024
Marginal	--	--	Pre-seed	+5		DEX	May 16, 2024
MITO Mitosis	$7.00 M	~$70.00 M	Seed Round	+8		DeFi	May 2, 2024
CARV Carv	$10.00 M	~$100.00 M	Series A	+7	--	Gaming	Apr 25, 2024
RUG.AI	$1.10 M	~$11.00 M	Pre-seed	+7		Artificial Intelligence (AI)	Mar 27, 2024
DreamOS	$2.10 M	~$21.00 M	Seed Round	+7		Blockchain Service	Mar 9, 2024
Synnax Technologies	$1.00 M	~$10.00 M	Pre-seed	+9	--	Artificial Intelligence (AI)	Mar 6, 2024

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